speaker-photo

Dr. Sandeep Chavan

B.A.M.S.; M.D. Ayurved (Rasashastra), Ph.D. Scholar (Ayurveda- Nutrition and Food Science)

Research Officer, Bharatiya Sanskriti Darshan Trust’s Integrated Cancer Treatment and Research Centre, Wagholi, Pune
Bhasma Section In-charge and R&D In-charge, Atharva Nature Healthcare Pvt Ltd, Wagholi, Pune

4:00 pm to 4:10 pm

Saturday 10th December 2022

Drug standardization and preclinical studies of herbo metallic Ayurvedic medicines for cancer treatment

Major research and scientific fields of interest:

  • Preparation and Standardization of various categories of Ayurvedic medicines
  • Ayurvedic Pharmaceutical Research pertaining to Standardization of Raw Materials-In process and Finished Products.
  • Product Development, process validation and Drug Research Protocol preparation of herbal and herbo-mineral metallic for various ailments especially Cancer.
  • Toxicity, stability and mechanistic studies of Ayurvedic formulations.

Publications:

h-index: 1, Citations: 5, since 2018.

  1. Sandeep Chavan, Sonali Tayade, Vidya Gupta, Vineeta Deshmukh, Sadanand Sardeshmukh. Pharmaceutical standardization and physicochemical characterization of traditional Ayurvedic marine drug: Incinerated conch shell (Shankha Bhasma); Marine Drugs; 2018, 16 (11), 450. https://doi.org/10.3390/md16110450.
  2. Sandeep Chavan, Sushama Bhuvad, Bhagyashri Kumbhlakar, Jyoti Auti, Tanhaji Walunj, Shridevi Pathak, Rahul Tanpure, Shweta Gujar, Jagdish Shinde, Arvind Kulkarni, Vidya Gupta, Vineeta Deshmukh, Sadanand Sardeshmukh; Antimicrobial and antioxidant potential of a standardized Ayurvedic formulation explains its clinical efficacy as gargles in post-radiotherapy oral cancer patients, Journal of Herbal Medicine 30 (2021) 100510. https://doi.org/10.1016/j.hermed.2021.100510
  3. Kumbhalkar B, Walunj T, Chavan S, Gupta V, Deshmukh V, Sardeshmukh S. Simultaneous identification and estimation of glycyrrhizin, glabridin, and 18β‐glycyrrhetinic acid in de‐glycyrrhized Ayurvedic lipid‐based formulation of Glycyrrhiza glabra using dual wavelength reverse phase‐high‐performance liquid chromatography; Journal of Separation Science Plus (Cover page); 2020, 3 (10), 460-471. https://doi.org/10.1002/sscp.202000015.
  4. Sandeep Chavan, Sadanand Sardeshmukh, Vineeta Deshmukh, Sukumar Sardeshmukh. Standardization of Kamdudha Rasa to understand the mechanism of action as adjunct treatment in management of chemotherapy and radiotherapy side effects- Journal of Ayurveda and Integrative Medicine (Conference abstract), 2018, 9 (2) (S1), S29 (SJR- 0.315). https://doi.org/10.1016/j.jaim.2018.02.126.
  5. Chavan Sandeep, Gupta Vidya, Deshmukh Vineeta, Sardeshmukh Sadanand; Pharmaceutical standardization and physicochemical characterization of traditional ayurvedic mineral drug red ochre roasted in cow’s ghee (Shuddha Gairik). Indian Journal of Traditional Knowledge 2022, 21(2), 303-316. http://op.niscair.res.in/index.php/IJTK/article/view/31007
  1. Sandeep Chavan, Study of Nutritional And Health Benefits of Grapes In Indian Diet, Mahratta 2022, May 1(1), 1-7. http://mahratta.org/CurrIssue/2022_May/6.%20Study%20of%20nutritional%20and%20health%20benefits%20of%20grapes%20in%20Indian%20diet-%20Sandeep%20Chavan.pdf
  1. Sandeep Chavan, Sonali Pareek, Vineeta Deshmukh, Sadanand Sardeshmukh. Identification of Guduchi Sattva by Microscopy- published in “ASHWASAN IV” by BSDT’s Integrated Cancer Treatment and Research Centre, Wagholi, Pune (2013)

Patents:

  1. Inventor: Full specifications for “Herbal Composition for oligospermia” vide application no. 201721012712 dated 08/04/2017 and published on 12/10/2018.
  2. Involved in drafting and drug specifications of 10 Indian and 4 International patents filed by Dr. S. P. Sardeshmukh and Dr. Vineeta V. Deshmukh from Bharatiya Sanskriti Darshan Trust, Wagholi, Pune. 

Award:

“Da. Va. Shendye Rasaushadhi Puraskar 2020” declared by the Maharshi Annasaheb Patwardhan Vaidyakiya Samiti of Khadiwale Vaidyak Samshodhan Sansthan, Pune.

 Current research activities:

  1. Drug Standardization of 14 herbal and herbo-mineral preparations with respect to development of protocol, preparation, data curation and data analysis.
  2. Co- Principal Investigator in toxicity studies of protocols used in Triple Negative Breast Cancer, BRCA 1/2 positive breast cancer, chemotherapy side effects in breast cancer and radiotherapy side effects in oral cavity cancer patients in collaboration with Advanced Centre for Treatment, Research and Education in Cancer, Kharghar, Navi Mumbai.
  3. Developed Drug Standardization Laboratory at BSDT’s ICTRC with advanced instrument like HPLC, GC, ICPOES and Microwave Digestion system.
  4. Co-investigator- Studies to explore novel applications of Ayurvedic formulations used in the treatment of neural ailments” at Haffkine Institute for Training, Research and Testing, Parel, Mumbai-400012.
  5. Immunomodulatory activity of Suvarna Bhasmadi Vati in Swiss albino mice

Conferences/ Seminars Presentations related to Cancer:

  • International Conference on Medicinal, Aromatic and Neutraceutical plants from Mountainous Areas (2019)
  • 14th Indo-Australian Biotechnology Conference “Emerging modalities to improve cancer outcomes” (2018)
  • Amrita Samyogam 2017, International Conference on Integrative Ayurveda and Modern Medicine- Cancer Section (2017)
  • Seminar and Awareness Workshop for students on Integrative Oncology (2015)
  • Completed several workshops and trainings for hand-on training of ICPOES, GC and HPLC; interpretation of instrumental methods like UV-VIS, FTIR, BET Surface Area, Particle Size Distribution, Zeta Potential Measurement, Contact Angle Measurement, XRF and FESEM; Good Clinical Practice; science writing and standardization of Ayurvedic medicines
  • Involved in teaching as guest speaker and resource person in Japan, Tilak Maharashtra Vidyapeeth, Dhee Ayurved, Sri Lanka and Bharatiya Sanskriti Darshan Trust.
  • Volunteering as reviewer in scholarly journals
  • Participated in several international exhibitions in Japan, Dubai, Sri Lanka and Malaysia
  • Socially active as participation in free health check-up camps, vaccination awareness and medicinal plantation drives